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A welcome message from the Chair of the Consortium
The focus and the work product of this Consortium is dedicated to all members of the Armed Forces, especially our Wounded Warriors.
The Major Extremity Trauma Research Consortium is funded through cooperative agreements with the United States Army Institute of Surgical Research (USAISR) Orthopaedic Extremity Trauma Research Program (OETRP) (Award # W81XWH-09-2-0108) and the DOD Peer Reviewed Orthopaedic Research Program (PRORP) of the Congressionally Directed Medical Research Program (CDMRP) (Award # W81XWH-10-2-0090).
Welcome to the METRC Website
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The Major Extremity Trauma Research Consortium (METRC) was established in September of 2009 with funding from the Department of Defense (DOD). It consists of a network of clinical centers and one data-coordinating center that works together with the DOD to conduct multi-center clinical research studies relevant to the treatment and outcomes of orthopaedic trauma sustained in the military. The overall goal of the Consortium is to produce the evidence needed to establish treatment guidelines for the optimal care of the wounded warrior and ultimately improve the clinical, functional and quality of life outcomes of both service members and civilians who sustain high energy trauma to the extremities. |
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The METRC Consortium
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METRC Studies
CORE AREAS OF RESEARCHMETRC will initially focus its efforts on research relevant to the early, acute treatment of major limb trauma. Over time, the Consortium will leverage its infrastructure to address other priority topics of relevance to both the acute care and rehabilitation of the wounded warrior and civilian trauma patient.
Priorities for investigation will be established in six core areas:
FIXIT StudyThis study will compare two standard options for treating severe open tibia fractures: internal fixation with a nail or plate and external ring fixation.
Read more about the FIXIT study here. pTOG StudyThe purpose of this study is to determine if rhBMP-2, a bone graft substitute, is as effective as using bone from the hip (iliac crest autograft) to help promote healing of open, tibia fractures with a bone defect.
Read more about the pTOG study here. BIOBURDEN StudyThe primary objective of this study is to characterize the contemporary extremity wound “bioburden” at the time of definitive wound coverage or closure of severe extremity wounds employing new polymerase chain reaction PCR technology. We will also determine the relationship of subsequent infections to the initial bioburden screen as defined by both PCR technology and standard microbiology techniques.
Read more about the BIOBURDEN study here. POvIV StudyThe goal of this study is to investigate the efficacy of oral (par oris - PO) antibiotic therapy versus intravenous (IV) systemic antibiotics in the treatment of acute infection after plate fixation of fractures.
Read more about the POvIV study here. PACS StudyThe long-term objective of this research is to develop a tool that can aid clinicians in making a timely and accurate diagnosis of acute compartment syndrome (ACS) so that early fasciotomy can be done and unnecessary fasciotomy avoided.
Read more about the PACS study here. OUTLET StudyThe purpose of this study is to compare 18 month functional outcomes and health related quality of life (HRQoL) of patients undergoing salvage versus amputation following severe distal tibia, ankle and/or foot injuries with major soft tissue, bone and/ or ankle articular surface loss.
Read more about the OUTLET study here. TCCI StudyThis study will evaluate the effectiveness of the Trauma Collaborative Care Intervention (TCCI) in improving long-term functional and quality of life outcomes for service members and civilians with severe, lower extremity trauma.
Read more about the TCCI study here. PAIN StudyThe objective of this study is to compare the efficacy of standard pain management vs. standard pain management combined with use of perioperative pregabalin (Lyrica) or ketorolac (Toradol) in the treatment of severe lower limb fractures.
Read more about the PAIN study here. APS StudyThe principal aim of this study is to determine the efficacy of Antibacterial Plate Sleeves (APS) in treating fractures at-risk of infection.
Read more about the APS study here. |
METRC Clinical Sites
METRC is a collaboration of 22 Core Civilian Trauma Centers, 4 Military Treatment Facilities, and 30 Satellite Centers throughout the United States, unified to identify and address critical issues challenging the recovery of combat and civilian trauma patients.
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METRC Investigators
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Zachary V. Roberts, MD
Assistant Professor of Orthopaedic SurgeryZachary V. Roberts, MD, is an Assistant Professor in the Department of Orthopedic Surgery and Rehabilitation at the University of Oklahoma College of Medicine. He is a member of the American Academy of Orthopaedic Surgeons and AO North America.
Learn more about Dr. Roberts by reading his full bio... -
Renn Crichlow, MD
Orthopaedic Trauma SurgeonDr. Renn Crichlow, M.D., orthopaedic trauma surgeon at OrthoIndy. Dr. Crichlow’s research interests include pelvic fractures in multiple injured patients and the psychological effects of traumatic injuries.
Learn more about Dr. Crichlow by reading his full bio... -
Lisa K. Cannada, MD
Associate Professor of Orthopaedic SurgeryLisa K. Cannada, MD is Associate Professor of Orthopaedic Surgery at Saint Louis University Hospital. Her research interests include care of the orthopaedic trauma patient with emphasis on patient outcome studies, osteobiologics and biomechanical studies.
Learn more about Dr. Cannada by reading her full bio... -
Jackson Lee, MD
Chief of the Orthopaedic Surgery ServiceJackson Lee, MD is the Chief of the Orthopaedic Surgery Service at the LAC+USC Medical Center, in addition to serving as the Director of Orthopaedic Trauma Service. He is also Associate Professor of Clinical Orthopaedic Surgery at the University of Southern California, Keck School of Medicine.
Learn more about Dr. Lee by reading his full bio... -
CDR James Toledano, MD, MC, USN
Director of Pediatric Orthopaedics and Scoliosis SurgeryDr. Toledano is a native of New Orleans, LA. His interest continues to focus on care of musculoskeletal injuries. Currently, his position is Director of Pediatric Orthopaedics and Scoliosis Surgery at the Naval Medical Center in San Diego, California.
Learn more about Dr. Toledano by reading his full bio... -
Ellen MacKenzie, PhD
Professor and Chair
Health Policy and Management
Director of the METRC ConsortiumEllen MacKenzie, PhD is the Fred and Julie Soper Professor and Chair of the Department of Health Policy and Management of the Johns Hopkins Bloomberg School of Public Health. She is a graduate of the School of Public Health where she earned Master of Science and doctoral degrees in biostatistics. She holds joint appointments with the Departments of Biostatistics, Emergency Medicine and Physical Medicine and Rehabilitation.
Learn more about Dr. MacKenzie by reading her full bio... -
Daniel O. Scharfstein, ScD
Professor of BiostatisticsDaniel O. Scharfstein, PhD is Professor of Biostatistics and the director of graduate studies in Biostatistics at the Johns Hopkins Bloomberg School of Public Health. He received his doctoral degree in Biostatistics from the Harvard School of Public Health, where he also completed an 18 month post-doctoral fellowship.
Learn more about Dr. Scharfstein by reading his full bio...
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Andrew R. Burgess, MD
Chief of Orthopaedic TraumaAndrew R. Burgess, MD, is a Professor and Vice-Chairman of the Department of Orthopaedic Surgery at The University of Texas Medical School at Houston, where he also serves as Chief of Orthopaedic Trauma. Dr. Burgess is also a Senior Affiliate Physician at Orlando Regional Medical Center.
Learn more about Dr. Burgess by reading his full bio... -
Peter A. Cole, MD
Chief of Orthopaedic SurgeryAs a full time Professor, of the University of Minnesota, practicing out of Regions Hospital, Dr. Cole has developed a worldwide reputation as an educator and researcher on advanced trauma topics including surgery of complex joint injuries, bone malunions, pelvic ring injuries. He is a leading expert in minimally invasive fracture care and complex shoulder girdle injury, and has the largest experience on record for the treatment of scapula fractures.
Learn more about Dr. Cole by reading his full bio... -
LCDR Robert Gaines, MD
Team Leader of TraumaLCDR Robert Gaines, MC, USN is currently the Team Leader of Trauma for the Department of Orthopaedic Surgery at Naval Medical Center-Portsmouth. Dr. Gaines most recently deployed with the Marines in Operation Kandjar, Hellmand Province, Afghanistan 2010.
Learn more about Dr. Gaines by reading his full bio... -
Joshua R. Langford, MD
Orthopaedic TraumatologistJoshua R. Langford, MD, an orthopaedic traumatologist, is part of the Orthopaedic Faculty Practice at ORMC. Dr. Langford is the only physician in Central Florida using special computer-aided dynamic frames (Taylor Spatial Frames) to repair fractures that have not healed, have become infected or have healed in poor alignment.
Learn more about Dr. Langford by reading his full bio... -
Milan K. Sen, MD, FRCSC
Chief of Orthopaedic TraumaCurrently, Dr. Sen is an Assistant Professor of Orthopaedic Surgery, Chief of Orthopaedic Trauma, and the Director of the Orthopaedic Trauma Fellowship at The University of Texas Medical School at Houston (UTHealth).
Learn more about Dr. Sen by reading his full bio... -
Andrew H. Schmidt, MD
Director of Clinical ResearchDr. Schmidt is a Professor at the University of Minnesota and Faculty at Hennepin County Medical Center (HCMC) in Minneapolis, MN. He specializes in trauma care and adult reconstructive surgery. Dr. Schmidt is Director of Clinical Research at HCMC, and his research interests include compartment syndrome and musculoskeletal infection.
Learn more about Dr. Schmidt by reading his full bio... -
Andrew Pollak, MD
Chief of Orthopaedic Traumatology
Co-Chair of the METRC ConsortiumDr. Pollak is Chief of Orthopaedic Traumatology and Associate Director of Trauma at the R Adams Cowley Shock Trauma Center, University of Maryland Medical Center. He currently chairs the Extremity War Injuries Project Team for the AAOS and is President-Elect of the Orthopaedic Trauma Association.
Learn more about Dr. Pollak by reading his full bio... -
James Jackson Hutson Jr., MD
Associate Clinical ProfessorJames Jackson Hutson Jr. MD practices Orthopedic Trauma Reconstruction Surgery at the University of Miami Ryder Trauma Center, Jackson Memorial Hospital, Miami, Florida.
Learn more about Dr. Hutson by reading his full bio... -
David J. Hak, MD, MBA
Associate ProfessorDr. Hak is actively involved in both clinical and basic science research relating to orthopaedic trauma, bone graft substitutes, and bone morphogenetic proteins. He currently serves on the Board of Directors of the International Society for Fracture Repair and the Orthopaedic Trauma Association.
Learn more about Dr. Hak by reading his full bio... -
J. Lawrence Marsh, MD
Carroll B. Larson Chair of Orthopedic SurgeryJ. Lawrence Marsh, MD is a Professor and the Carroll B. Larson Chair of Orthopedic Surgery and Director of the Orthopaedic Residency Training Program at the University of Iowa Hospitals and Clinics. His research interests are in Post Traumatic Osteoarthritis and his work is currently funded from NIH, OTA and the Arthritis foundation.
Learn more about Dr. Marsh by reading his full bio... -
Lisa Reider, MHS
Assistant Scientist
Health Policy and ManagementLisa Reider, MHS, is an Assistant Scientist in the Johns Hopkins Bloomberg School of Public Health (JHSPH), Department of Health Policy and Management. Ms. Reider is an epidemiologist with experience and expertise in coordinating multi-center interdisciplinary research studies.
Learn more about Ms. Reider by reading her full bio... -
J. Spence Reid, MD
Division Chief of Orthopaedic TraumaJ. Spence Reid, MD is a Professor of Orthopaedic Surgery and Division Chief of Orthopaedic Trauma at Penn State University's College of Medicine and Milton S. Hershey Medical Center. His research interests include all aspects of orthopaedic trauma care.
Learn more about Dr. Reid by reading his full bio... -
Gregory A. Zych, DO
Professor and Chief, Orthopaedic TraumaGregory A. Zych, D.O. is the Christine E. Lynn Distinguished Chair in Orthopaedic Trauma. He is the Chief of the Division of Orthopaedic Trauma, Professor of Orthopedics and Rehabilitation, Department of Orthopedics and Rehabilitation, Miller School of Medicine at the University of Miami.
Learn more about Dr. Zych by reading his full bio... -
Heather A. Vallier, MD
Associate Professor of Orthopaedic SurgeryHeather Vallier, MD is the Clyde L. Nash, Jr. Professor of Orthopaedic Education of Case Western Reserve University and an active member of the medical staff of The MetroHealth System. Dr. Vallier leads and contributes to various committees within the MetroHealth System. She also enjoys mentoring and advising and currently serves as the Director of Education in Orthopaedic Surgery at MetroHealth.
Learn more about Dr. Vallier by reading her full bio... -
J. Tracy Watson, MD
Chief of the Orthopedic Trauma ServiceDr. Watson is currently Professor of Orthopaedic Surgery and Chief of the Orthopedic Trauma Service at St. Louis University School of Medicine in St. Louis Missouri. Dr. Watson is considered one of North America’s experts in the area of distraction techniques for acute trauma and post traumatic applications.
Learn more about Dr. Watson by reading his full bio... -
Bruce J. Sangeorzan, MD
Professor and Vice Chair of OrthopaedicsDr. Sangeorzan is currently a Professor and Vice-Chair in the Department of Orthopaedics and Sports Medicine at the University of Washington and is Director of the Veterans Affairs Center of Excellence in Amputation Prevention and Prosthetic Engineering at the Seattle Division of the Puget Sound VA.
Learn more about Dr. Sangeorzan by reading his full bio... -
Theodore Miclau III, MD
Director of Orthopaedic Trauma
Theodore Miclau III, MD, is Vice Chairman and Director of Orthopaedic Trauma of the Department of Orthopaedic Surgery at the University of California, San Francisco, (UCSF). He currently serves on the Board of Directors for the Orthopaedic Trauma Association, Orthopaedic Research Society, and the American Academy of Orthopaedic Surgery.
Learn more about Dr. Miclau by reading his full bio... -
Roy Sanders, MD
Chief of OrthopaedicsDr. Sanders specializes in acute trauma care, and post-traumatic reconstruction, as well as foot and ankle surgery. He is the President of Florida Orthopaedic Institute, the largest orthopaedic practice in the State of Florida, a group he helped found in 1989. He is also the Director of the Orthopaedic Trauma Service, and Chief of Orthopaedics at Tampa General Hospital.
Learn more about Dr. Sanders by reading his full bio... -
Clifford Jones, MD, FACS
Director of Orthopaedic Clinical ResearchClifford Jones, MD is an Orthopaedic Trauma Surgeon and Director of Orthopaedic Clinical Research at the Spectrum Health Medical Center and Director of Orthopaedic Research for the Michigan State University Medical Education and Clinical Research Residency Program in Grand Rapids, Michigan.
Learn more about Dr. Jones by reading his full bio... -
Eben A. Carroll, MD
Assistant Professor of Orthopaedic SurgeryEben A. Carroll, MD is an Assistant Professor in the Department of Orthopaedic Surgery at Wake Forest University School of Medicine. His research interests include fractures in the elderly, pelvic and acetabular trauma, and ankle fractures.
Learn more about Dr. Carroll by reading his full bio... -
Robert V. O’Toole MD, MSME
Director of Clinical ResearchRobert V. O’Toole MD, MSME, is an attending orthopaedic surgeon at the R Adams Cowley Shock Trauma (STC) at the University of Maryland Medical Center and serves as the Director of Clinical Research for the Department of Orthopaedics at the University of Maryland School of Medicine.
Learn more about Dr. O'Toole by reading his full bio... -
Anna N. Miller, MD
Assistant Professor of Orthopaedic Surgery
Anna N. Miller, MD is an Assistant Professor in the Department of Orthopaedic Surgery and is the Assistant Director of Orthopaedic Trauma, as well as Associate Faculty with the Women’s Health Center of Excellence for Research, Leadership and Education at Wake Forest University School of Medicine.
Learn more about Dr. Miller by reading her full bio... -
William T. Obremskey, MD, MPH
Associate Professor of OrthopaedicsWilliam T. Obremskey, MD MPH, is the Director of Orthopaedic Trauma Research and Education at Vanderbilt University's Department of Orthopaedics. He has served as Chairman of the Orthopaedic Trauma Association’s Membership Committee, is currently the Chair of the OTA’s Committee on Evidence-Based Medicine, and a member of the Program Committee for the OTA.
Learn more about Dr. Obremskey by reading his full bio... -
LTC Joseph R. Hsu, MD
Chief of Orthopaedic TraumaDr. Hsu is the Chief of Orthopaedic Trauma, Research Director for Orthopaedic Surgery Service, and Assistant Program Director (Research), Orthopaedic Surgery Residency SAUSHEC San Antonio Military Medical Center at Brooke Army Medical Center.
Learn more about Dr. Hsu by reading his full bio... -
Michael Bosse, MD
Director of Orthopaedic Clinical Research
Chair of the METRC Consortium
Dr. Bosse is an Orthopaedic Trauma Surgeon and Director of Orthopaedic Clinical Research at the Carolinas Medical Center in Charlotte, North Carolina. After graduating from the U.S. Naval Academy in 1974, Dr. Bosse completed medical school at the University of Maryland. He served as the Chief of Orthopaedic Surgery on the Hospital Ship Comfort during Desert Storm.
Learn more about Dr. Bosse by reading his full bio... -
David C. Teague, MD
Professor of Orthopaedic SurgeryDavid C. Teague, MD is Professor and Chairman of the Department of Orthopedic Surgery and Rehabilitation at the University of Oklahoma College of Medicine. He currently serves as Chairman of the Orthopedic Trauma Association Education Committee, and is a member of the American College of Surgeons, Committee on Trauma.
Learn more about Dr. Teague by reading his full bio... -
Aaron T. Scott, MD
Assistant Professor of Orthopaedic SurgeryAaron T. Scott, MD is an Assistant Professor in the Department of Orthopaedic Surgery at Wake Forest University School of Medicine. Dr. Scott is a member of the Piedmont Orthopaedic Society, the American Orthopaedic Foot and Ankle Society, the American Academy of Orthopaedic Surgeons and the North Carolina Orthopaedic Association.
Learn more about Dr. Scott by reading his full bio... -
Robert D. Teasdall, MD
Professor of Orthopaedic SurgeryRobert D. Teasdall, MD is a Professor in the Department of Orthopaedic Surgery at Wake Forest University School of Medicine. Dr. Teasdall has been a member of the Orthopaedic Trauma Association since 1994 and has served as Chair for the OTA Classifications Committee and is the Medical Director of the Orthopaedic Trauma Service at Wake Forest University School of Medicine.
Learn more about Dr. Teasdall by reading his full bio... -
Robert McGuire, MD
Chairman Orthopaedic Surgery & RehabDr. McGuire is the Chair of Orthopaedic Surgery and Rehabiliation at UMMC, and has served as Chairman of AO Spine North America from December 2006 until December 2009. Dr. McGuire completed an internship and residency in orthopedics at Naval Hospital, Portsmouth, Virginia, and he served as co-director of spine surgery service there until 1990 when he joined the UMC faculty.
Learn more about Dr. McGuire by reading his full bio... -
Renan C. Castillo, PhD
Assistant Professor
Health Policy and ManagementRenan C. Castillo, PhD is an Assistant Professor in the Department of Health Policy and Management, where he also received his doctoral training. Dr. Castillo is a health services researcher with expertise in the study of disability and trauma outcomes, and extensive experience coordinating multi-institutional studies in the trauma setting.
Learn more about Dr. Castillo by reading his full bio... -
COL Romney C. Andersen, MD
Chairman of Orthopaedic SurgeryCOL Romney C. Andersen, MD, is the Chairman of Orthopaedic Surgery at the Walter Reed National Military Medical Center in Bethesda, MD. He is an Orthopaedic Trauma Surgeon who focuses on reconstructions of complex combat related injuries. Dr. Andersen’s academic interests lie in caring for the combat injured casualty.
Learn more about Dr. Andersen by reading his full bio... -
William J.J. Ertl, MD
Associate Professor of Orthopaedic SurgeryWilliam Ertl, MD, is an Associate Professor of Orthopaedic Surgery specializing in Orthopaedic Traumatology at the University of Oklahoma College of Medicine and currently serves as Medical Director of the Adult OR of OU Medical Center.
Learn more about Dr. Ertl by reading his full bio... -
Paul Tornetta III, MD
Director of Orthopaedic TraumaPaul Tornetta III, MD, is the Director of Orthopaedic Trauma at the Boston Medical Center and Professor, Vice Chairman, and Residency Program Director of Orthopaedic Surgery at the Boston University School of Medicine. He completed his medical degree, internship and orthopaedic residency training at the State University of New York Health Science Center.
Learn more about Dr. Tornetta by reading his full bio... -
Lt Col Wade Gordon, MD
Chief of the Orthopaedic Trauma ServiceLt Col Wade Gordon, MD, currently serves as Chief of the Orthopaedic Trauma Service at the Walter Reed National Military Medical Center in Bethesda, MD. His practice focuses on the care of combat extremity injuries, particularly limb salvage, deformity correction, and amputation care.
Learn more about Dr. Wade by reading his full bio...
